Friday, October 29, 2010

scrofuloderma


*Result from break of skin overlying a tuberculous focus,usually at a lymph node but also at the skin over infected bones or joints.
*Historically a high prevalence was found in children infected with m.bovis .
*The oral or tonsillar primary lesion progresses to cervical adenitis, formation of cold abscesses and secondary breakdown of the overlying skin.
*Tubercle bacilli can be isolated from purulent discharge.
*Tuberculin sensitivity is usually marked. 
*Spontaneous healing can occur but often takes years. Lupus vulgaris may develop in the vicinity of healing scrofuloderma.
*Metastatic tuberculous abscesses is a variant of scrofuloderma that occurs following hematogenous  spread of mycobacteria to skin in tuberculin sensitive individuals.
*Typically occurs in malnourished children or severely immunosupressed patients.

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