Friday, October 29, 2010

Lupus vulgaris


*A chronic and progressive form of cuteneous TB that occurs in tuberculin sensitive patients. In most series it is the most common form of cut. TB.
*Lesion appears in normal skin as a result of direct extension of underlying tuberculous foci, of lymphatic or hematogenous spread, after primary inoculation, BCG vaccination or in scars of old scrofuloderma.
*Lesion mostly invove the head and neck.
*Reappearance of new nodules within a previously atrophic or scarred lesion is characteristic.
*Cartilage within the affected area is progressively destroyed(lupus vorax)
*Bone is usually spared.
*Clinical variants include;
*a)plaque form
*b)ulerating
*c)vegetative
*d)nodular
*Lesions often persist for years before diagnosis
*And can be disfiguring
*Patients with lupus vulgaris and PTB have a 4-10 fold higher mortality than PTB alone.
*In long standing lupus vulgaris,squamous cell carcinoma can occur and be confused with the disease itself.http://www.answers.com/topic/lupus-vulgaris

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